Ginseng Saponin Antitumor Substances Declaration
•Ginsenoside Rh2 prophylaxis and antitumor
Ginsenoside Rh2 monomer has an inhibitory effect on the growth of cancer cells, and can induce tumor cell apoptosis, reverse abnormal differentiation of tumor cells, and resist tumor metastasis. Combined with chemotherapy drugs, it can increase the efficacy and reduce the toxicity.
•Ginsenoside monomer Rg3 prophylaxis and antitumor
It can inhibit the adhesion and invasion of tumor cells, and prevent the formation of new blood vessels of cancer cells, so as to inhibit the growth, spread and metastasis of tumor, which has significant anti-cancer function. It can significantly improve the decline of white blood cells caused by radiotherapy, chemotherapy and surgery, and make the hemorheology tend to be normal. It can improve the human body function and immune function, and it has significant effects with surgery, radiotherapy and chemotherapy.
•Ginsenoside Monomer Rg5 Prophylaxis And Antitumor
Rg5 can induce apoptosis of a variety of tumor cells. Rg5 extracted from black ginseng has been verified in human breast cells. Rg5 can also induce apoptosis of a variety of cervical cancer cells and DNA damage.
•Ginsenoside Rh3 Prophylaxis And Antitumor
Ginsenoside Rh3 can inhibit the proliferation and induce apoptosis of human colon cancer cell SW480 in a dose-dependent and time-dependent manner.
•Ginsenoside APPD Prophylaxis And Antitumor
20(S)- propanax ginseng diol (aPPD) is an active ingredient with drug efficacy produced by ginsenoside through the glycosylation and activation of gastrointestinal flora, which has a broad spectrum of anti-tumor effect. In recent years, William Jia's research group from the university of British Columbia has conducted a series of studies on the anti-tumor activity of aPPD in vivo and in vitro, and found that it has dual pharmacological effects. On the one hand, it can directly kill tumor cells and promote their apoptosis. On the other hand, it can protect neurons from cellular poisons.
Ginsenoside Rh1 Prophylaxis And Antitumor.